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KMID : 0377219810060010079
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Medical Journal of Chosun Univercity
1981 Volume.6 No. 1 p.79 ~ p.91
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Clinical Observation and the Therapeutic Effect of Intralesiolnal Injection of Triamcinolone in Herpes Zoster
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Choi Kyu-Cherl
Hwang Sun-Wook
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Abstract
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Herpes zoster is an acute infection of varicellar-zoster (V-Z)virus characterized by groups of vesicles and papules on the erythematous base along the corresponding dermatome of the involved segment in the cranial or spinal sensory ganglia. The treatment of herpes zoster aims at the symptomatic control of neuragia. One hundred and ninety five cases of herpes zoster were clinically observed at the Department of Dermatology of Chosun University Hospital from April 15, 1971 through September 30, 1980. The therapeutic effect of intralesional injection of triamcmolone on herpetic neuralgia was compared with those of systemic corticosteroid and the symptomatic analgesics. The results obtained were as follows : 1) The incidence of herper zoster versus the total number of outpatients wad between 0.50% and 1.89% (on an average, 1.30%) and there was no sexual difference of its incidence. 2) There were no marked monthly or seasonal differences in the incidence of herpes zoster. 3) The herpes zoster was frequently seen in the age of 20 to 29 years old. Considering the age distribution of population in Kwang-ju city. however. its incidence seems to increase with age. 4) Fifteen cases(9.6%.) of the herpEs zoster were seen to be combIned with chronic diseases such as pulmonary tuberculosis, diabetes mellitus and hypsrtension. 5) Herpes zoster was located in the thoracic (46.6%,), trigeminal, cervical, lumbar, sacral and facial nerve dermatomes in that order of frequency. 6) Postherpetic neuralgia was the most common complication with its incidence increasing with age. 7) Thirty nine cases with herpes zoster had intralesional injection with triamcinolone with the following results. Eleven (28.2%) had similar reaction as those treated with systemic corticosteroid and symptomatic analgesics whereas 28 (71.8%) had a more_effective response.
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KEYWORD
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Triamcinolone, Clinical observation
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